Microme is a new bioinformatics infrastructure for the curation and integration of bacterial reactions and pathways, for genome annotation and for the reconstruction of metabolic networks. The first release includes reactions and pathways from Escherichia coli K-12, projected to Pseudomonas putida, Salmonellea enterica and 21 other diverse bacterial species.

Microme exploits Ensembl software to support genome browsing, and Reactome software to support the management and display of pathway data.

In future releases, we will increase the range of reference pathways and reactions, add new species to the projected mechanism, and develop and present stoichiometric models for the species in the resource. These models (and the lessons learnt from developing and experimentally testing them) will be used to refine the reference data. Other activities in the Microme project include the comparative evolutionary study of pathways, and the exploration of biotechnological potential.

Microme is a 15-partner project funded by the Framework 7 programme of the European Commission.

Publications

Release notes